Dr Matthew Bottomley
Transplant Physician
Dr Bottomley is a consultant nephrologist at the Oxford Kidney and Transplant Unit, Churchill Hospital, Oxford, and is a clinician-scientist at the Chinese Academy of Medical Sciences Oxford Institute (COI), University of Oxford. He has a particular interest in long-term complications seen after kidney transplant, including the development of skin cancer. His research group work on identifying new clinical and immunological biomarkers to assist risk stratification, as well as exploring changes in cell and signalling pathways underpinning the immune response to cutaneous squamous cell carcinoma (CSCC) (Bottomley et al, J Am Soc Nephrol, 2016; Bottomley et al, Front Immunol, 2022; Ahuja et al, Nature Communications, 2023). He leads the spatial transcriptomic hub at the COI, utilising this novel approach to explore cell behaviour within tissue.
He is the Principal Investigator for the COAST Study, a multicentre cohort study to evaluate contemporary management and outcomes after first CSCC in kidney transplant recipients. He has previously published consensus recommendations regarding the management of organ transplant recipients with first CSCC (Bottomley et al, Transpl Int, 2022).